Research Associate 1, In Vivo for Skeletal and CNP Therapeutic Area

Company: BioMarin Pharmaceutical Inc.
Location: Petaluma
Posted on: December 31, 2025

Job Description:

Who We Are For more than two decades, going our own way has led to countless breakthroughs, bettering the lives of those suffering from rare genetic disease. In 1997 we were founded to make a big difference in small patient populations. Now we seek to make an even greater impact by applying the same science-driven, patient-forward approach that propelled our last 25 years of drug development to larger genetic disorders, as well as genetic subsets of more common conditions. Through our unparalleled expertise in genetics, drug discovery and development, we will continue to develop targeted therapies that address the root cause of the conditions we seek to treat. Applying our knowledge to make a transformative impact is not just a calling, but an obligation to those who will benefit most. The end goal has always been better lives and now we can reach more people in need. Our Culture Our desire to make a positive impact on our patients extends to our employees and BioMarin is committed to fostering an inclusive environment where every person feels seen, valued, and heard - so employees can thrive in all areas of their lives, in and outside of work. We seek to provide an open, flexible, and friendly work environment to empower people and to provide them with the ability to develop their long-term careers. Ultimately, we want to be an organization where people enjoy coming to work and take pride in our efforts to help patients. BioMarin's Research & Development group is responsible for everything from research and discovery to post-market clinical development. Research & Development involves all bench and clinical research and the associated groups that support those endeavors. Our teams work on developing first-in-class or best-in-class therapeutics that provide meaningful advances to patients. Come join our team and make a meaningful impact on patients' lives. Position Overview: We are seeking a motivated Research Associate I with in vivo experience to join the Skeletal and CNP Therapeutic Area group in vivo team to design and execute key studies to transform the lives of people with rare musculoskeletal diseases. The primary role of the Research Associate I will be assisting with the execution of in vivo studies as part of the in vivo team. They will work collaboratively across Research group in the Skeletal and CNP Therapeutic Area group as well as other therapeutic areas as needed to execute project strategies for in vivo testing of novel therapeutics. The successful candidate will have a background in animal handling, in vivo techniques and demonstrated experience in the use of animal model systems in research. Experience with rodent in vivo models of disease and a collaborative mindset is highly preferred. Experience with skeletal disease biology is desirable. While some industry experience is a plus, it is not required. The successful candidate will contribute to in vivo model evaluation and project teams that support the project goals. Strong written communication skills are critical for IACUC protocols, communicating study results, monitoring in vivo studies and tissue collection, and sample management. The successful candidate will have experience with multiple methods of dosing techniques (IM, IP, IV, SC, PO), Necropsy, tissue collection and preferred experience with other in vivo analytic techniques including gait analysis, mechanical evaluation of bone, histology, computerized tomography and IVIS imaging. The ideal candidate will have a Bachelor’s or equivalent scientific degree in Biology or related science. The ideal candidate will have hands-on experience with dosing and data collection in animal models of disease, a proven track record of high-quality science, proficiency with in vivo methods such as administration of test articles, perfusion and tissue collection, blood collection, with rodent surgical experience preferred. Responsibilities: Support Research Program • Conduct in vivo dosing support and execution of studies including IV, IM, SC, IP, and PO dosing for research on genetic skeletal diseases and CNP therapeutic indications • Contribute to novel therapeutic programs based on innovative, ground-breaking discoveries that could lead to new, high-impact opportunities for patients • Participate and collaborate in writing, review and contribution to study synopses, protocols, study reports and regulatory documents • Collaborate with various BioMarin functions to collaboratively ensure timely progression of projects • Excellent written and verbal communication • Ability to build and foster productive cross-functional collaborations both within and external to BioMarin • Execute hands-on responsibilities including but not limited to animal handling and restraint (rodents), administration via various routes of administration, including intravenous (tail-vein), in-life animal health monitoring and measurements, clinical observations, sample collection and processing, and accurate data collection. In addition, providing daily care and monitoring of mice or rats, including health checks and documentation, will also be required. • Follow all institutional, local, and federal regulations regarding animal care and use. Adhere to safety protocols and maintain a clean and organized work environment. Maintain detailed and accurate records of all procedures and animal health status including adverse study events. Meticulous electronic lab notebook documentation. • Communicate experimental plans and results to the project team. Support product development and regulatory filings for pivotal preclinical studies. • Follow instructions and work independently to effectively manage time and prioritize tasks to ensure all assignments are completed on or before deadlines. • Share your knowledge and understanding with other team members • Document experimental methods and outcomes using Electronic Lab Notebooks and generation/maintenance of technical procedure documents and SOPs. • Willingness to work on site full time including off hours and weekends based on study needs. General requirements for the position: • Strong analytical, problem-solving, and decision-making skills • Understanding of genetically engineered models, breeding of rodents • Excellent oral and written communication skills • Passion for contributing your scientific skills to develop therapies for patients in need • Must be able to utilize computer databases for data analysis, data entry, and point of care observations • Must be able to work under time constraints with minimal direction of day-to-day responsibilities, including collaboratively working with multidisciplinary teams • Must be able to work with external regulatory agencies and accreditation groups • Some "off-core business hours" work required • Complete all company training requirements • Perform all work per designated safety standards and comply with Personal Protective Equipment requirements and occupational health to perform work tasks • This position is an on-site critical required position Education and Experience Requirements: • Bachelor’s degree in a related subject area or equivalent amount of previous related experience in in vivo study execution * Hands-on experience with animal handling preferred if inclusive of rodent in vivo work. * RA 1 will typically have a minimum of 2 years relevant experience This position is full-time on-site and based in Petaluma, CA with occasional work on site in San Rafael, CA Note: This description is not intended to be all-inclusive, or a limitation of the duties of the position. It is intended to describe the general nature of the job that may include other duties as assumed or assigned. Equal Opportunity Employer/Veterans/Disabled An Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, or protected veteran status and will not be discriminated against on the basis of disability.

Keywords: BioMarin Pharmaceutical Inc., Fremont , Research Associate 1, In Vivo for Skeletal and CNP Therapeutic Area, Science, Research & Development , Petaluma, California